کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3358394 1688158 2016 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Ten key points for the appropriate use of antibiotics in hospitalised patients: a consensus from the Antimicrobial Stewardship and Resistance Working Groups of the International Society of Chemotherapy
ترجمه فارسی عنوان
ده موارد کلیدی برای استفاده مناسب از آنتی بیوتیک ها در بیماران بستری: هماهنگی گروه های مدیریت و ضد مقاومت در برابر انجمن های بین المللی شیمی درمانی
کلمات کلیدی
مقاومت ضد میکروبی، نظارت بر ضد میکروبی، استفاده عاقلانه از آنتی بیوتیک ها، درمان ترکیبی
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروبیولوژی و بیوتکنولوژی کاربردی
چکیده انگلیسی


• The misuse of antibiotics and its related bacterial resistance is a growing concern that deserves a wide variety of interventions.
• Education of prescribers using these ten key points seems an essential initiative.
• This 10 key points would guide prescribers to a better use of antibiotics, as one necessary step to tackle antimicrobial resistance.

The Antibiotic Stewardship and Resistance Working Groups of the International Society for Chemotherapy propose ten key points for the appropriate use of antibiotics in hospital settings. (i) Get appropriate microbiological samples before antibiotic administration and carefully interpret the results: in the absence of clinical signs of infection, colonisation rarely requires antimicrobial treatment. (ii) Avoid the use of antibiotics to ‘treat’ fever: use them to treat infections, and investigate the root cause of fever prior to starting treatment. (iii) Start empirical antibiotic treatment after taking cultures, tailoring it to the site of infection, risk factors for multidrug-resistant bacteria, and the local microbiology and susceptibility patterns. (iv) Prescribe drugs at their optimal dosing and for an appropriate duration, adapted to each clinical situation and patient characteristics. (v) Use antibiotic combinations only where the current evidence suggests some benefit. (vi) When possible, avoid antibiotics with a higher likelihood of promoting drug resistance or hospital-acquired infections, or use them only as a last resort. (vii) Drain the infected foci quickly and remove all potentially or proven infected devices: control the infection source. (viii) Always try to de-escalate/streamline antibiotic treatment according to the clinical situation and the microbiological results. (ix) Stop unnecessarily prescribed antibiotics once the absence of infection is likely. And (x) Do not work alone: set up local teams with an infectious diseases specialist, clinical microbiologist, hospital pharmacist, infection control practitioner or hospital epidemiologist, and comply with hospital antibiotic policies and guidelines.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Antimicrobial Agents - Volume 48, Issue 3, September 2016, Pages 239–246
نویسندگان
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