کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3359841 | 1591839 | 2010 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Characterisation of breakthrough invasive mycoses in echinocandin recipients: an evidence-based review
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موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
میکروبیولوژی و بیوتکنولوژی کاربردی
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![عکس صفحه اول مقاله: Characterisation of breakthrough invasive mycoses in echinocandin recipients: an evidence-based review Characterisation of breakthrough invasive mycoses in echinocandin recipients: an evidence-based review](/preview/png/3359841.png)
چکیده انگلیسی
The echinocandins have emerged as important antifungal agents in the current era. Despite their potent antifungal activity, breakthrough invasive mycoses occur in echinocandin recipients, however their precise incidence and causative pathogens are not well delineated. This review shows that breakthrough mycoses occur in 2.4% of patients receiving echinocandins as prophylaxis and are predominantly due to non-albicans Candida spp. and less frequently to invasive aspergillosis. Candida isolates demonstrating reduced susceptibility occurred following prolonged exposure to the echinocandins, primarily in severely immunocompromised patients, and manifested as recurrent episodes of candidaemia or invasive candidiasis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Antimicrobial Agents - Volume 35, Issue 3, March 2010, Pages 211–218
Journal: International Journal of Antimicrobial Agents - Volume 35, Issue 3, March 2010, Pages 211–218
نویسندگان
Hsin-Yun Sun, Nina Singh,