کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3360932 1591874 2008 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Isolation and characterisation of two novel coliphages with high potential to control antibiotic-resistant pathogenic Escherichia coli (EHEC and EPEC)
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروبیولوژی و بیوتکنولوژی کاربردی
پیش نمایش صفحه اول مقاله
Isolation and characterisation of two novel coliphages with high potential to control antibiotic-resistant pathogenic Escherichia coli (EHEC and EPEC)
چکیده انگلیسی

Two newly isolated virulent coliphages (MVBS and MVSS) showed ability to lyse (form plaque on) a high percentage of pathogenic Escherichia coli strains of various serotypes and origins (292/310; 94.2%), whilst displaying low lytic (plaque-forming) capacity on non-pathogenic ECOR strains (MVBS and MVSS lysed 10/72 (13.9%) and 15/72 (20.8%) strains, respectively). In comparison, a higher percentage (196/310, 63.2%) of tested isolates exhibited resistance to a broad range of antibiotics. It was also observed that, in contrast to antibiotics, phage treatment did not induce Shiga toxin production. These findings suggest that the newly isolated bacteriophages have potential for biocontrol and as therapeutic agents for pathogenic E. coli (EHEC and EPEC) strains.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Antimicrobial Agents - Volume 31, Issue 2, February 2008, Pages 152–157
نویسندگان
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