کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3363638 | 1592112 | 2011 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Diagnosis of anal human papillomavirus infection: polymerase chain reaction or cytology? Diagnosis of anal human papillomavirus infection: polymerase chain reaction or cytology?](/preview/png/3363638.png)
SummaryObjectivesTo investigate the relationship between human immunodeficiency virus (HIV)-positive and HIV-negative patients engaging in promiscuous behaviors and anal human papillomavirus (HPV) infection diagnosed by polymerase chain reaction (PCR) and cytology.MethodsFifty-six HIV-positive patients and 49 HIV-negative patients who engaged in sexually promiscuous behavior were enrolled in the study. We performed cytological exams using the Pap smear and PCR for HPV-DNA detection, with identification of oncogenic strains. The 2001 Bethesda System terminology was used for the cytological exams. We also evaluated the immunologic status of the HIV-infected patients.ResultsPCR positivity for HPV-DNA was higher in the group of HIV-positive patients than in the group of HIV-negative patients with a statistically significant difference. In contrast we did not find any statistically significant difference by cytological exam. Oncogenic strains were equally distributed in the two groups.ConclusionsOur results indicate the importance of the cytological exam for anal HPV screening in the population at high risk of sexually transmitted disease and that HPV-DNA PCR can be used only as adjunct test.
Journal: International Journal of Infectious Diseases - Volume 15, Issue 4, April 2011, Pages e232–e235