کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
336429 547128 2014 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Contributions of sex, testosterone, and androgen receptor CAG repeat number to virtual Morris water maze performance
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی علوم غدد
پیش نمایش صفحه اول مقاله
Contributions of sex, testosterone, and androgen receptor CAG repeat number to virtual Morris water maze performance
چکیده انگلیسی

SummaryThe possibility that androgens contribute to the male advantage typically found on measures of spatial cognition has been investigated using a variety of approaches. To date, evidence to support the notion that androgens affect spatial cognition in healthy young adults is somewhat equivocal. The present study sought to clarify the association between testosterone (T) and spatial performance by extending measurements of androgenicity to include both measures of circulating T as well as an androgen receptor-specific genetic marker. The aims of this study were to assess the contributions of sex, T, and androgen receptor CAG repeat number (CAGr) on virtual Morris water task (vMWT) performance in a group of healthy young men and women. The hypothesis that men would outperform women on vMWT outcomes was supported. Results indicate that CAGr may interact with T to impact navigation performance and suggest that consideration of androgen receptor sensitivity is an important consideration in evaluating hormone–behavior relationships.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Psychoneuroendocrinology - Volume 41, March 2014, Pages 13–22
نویسندگان
, , , ,