کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3380195 1220198 2011 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Validity of joint space width measurements in hand osteoarthritis
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی ایمونولوژی، آلرژی و روماتولوژی
پیش نمایش صفحه اول مقاله
Validity of joint space width measurements in hand osteoarthritis
چکیده انگلیسی

SummaryObjectiveTo investigate the validity of joint space width (JSW) measurements in millimeters (mm) in hand osteoarthritis (OA) patients by comparison to controls, grading of joint space narrowing (JSN), and clinical features.MethodsHand radiographs of 235 hand OA patients (mean age 65 years, 83% women) and 471 controls were used. JSW was measured with semi-automated image analysis software in the distal, proximal interphalangeal and metacarpal joints (DIPJs, PIPJs and MCPJs). JSN (grade 0–3) was assessed using the osteoarthritis research society international (OARSI) atlas. Associations between the two methods and clinical determinants (presence of pain, nodes and/or erosions, decreased mobility) were assessed using Generalized Estimating Equations with adjustments for age, sex, body mass index (BMI) and mean width of proximal phalanx.ResultsJSW was measured in 5631 joints with a mean JSW of 0.98 mm (standard deviation (SD) 0.21), being the smallest for DIPJs (0.70 (SD 0.25)) and largest for MCPJs (1.40 (SD 0.25)). The JSN = 0 group had a mean JSW of 1.28 mm (SD 0.34), the JSN = 3 group 0.17 mm (SD 0.23). Controls had larger JSW than hand OA patients (P-value < 0.001). In hand OA, females had smaller JSW than men (β −0.08, (95% confidence interval (95% CI) −0.15 to −0.01)) and lower JSW was associated with the presence of pain, nodes, erosions and decreased mobility (adjusted β −0.21 (95% CI −0.27, −0.16), −0.37 (−0.40, −0.34), −0.61 (−0.68, −0.54) and −0.46 (−0.68, −0.24) respectively). These associations were similar for JSN in grades.ConclusionIn hand OA the quantitative JSW measurement is a valid method to measure joint space and shows a good relation with clinical features.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Osteoarthritis and Cartilage - Volume 19, Issue 11, November 2011, Pages 1349–1355
نویسندگان
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