Migraine Predicts Self-Reported Muscle Tension in Patients With Major Depressive Disorder

Background/ObjectiveThe aim of this study was to identify factors related to muscle tension in patients with major depressive disorder (MDD) with comorbid anxiety and migraine.MethodConsecutive psychiatric outpatients with MDD were enrolled. Self-reported muscle tension (SMT) during the previous week was evaluated with a 0–10 scale.ResultsOf 135 participants with MDD, 63 (46.7%) had migraine. Multiple-regression analyses showed that migraine and headache intensity were two major independent factors related to SMT.ConclusionFurther studies on musculoskeletal symptoms in MDD should not neglect the impact of migraine.