کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3385630 1220616 2009 15 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Enfermedades osteocondensantes: una nueva visión clínico-radiológica soportada en la genética y la inmunoosteología
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی ایمونولوژی، آلرژی و روماتولوژی
پیش نمایش صفحه اول مقاله
Enfermedades osteocondensantes: una nueva visión clínico-radiológica soportada en la genética y la inmunoosteología
چکیده انگلیسی
The alterations in osseous remodeling lead to the increase or decrease of the osseous mass, generating damage to the osseous micro-architecture, which increases the risk of fracture. The pathologies with increase in osseous density lead to different genetically directed osteocondensing processes. The osteocondensing is currently explained by alteration in the function of the osteoclast, associated with a deficient function of the osseous resorption, an alteration in the osteoblast function, which generates an abnormal increase in the osseous formation, or a homeostatic imbalance between the two processes; the clinical and radiological expression of these diseases can take place in early stages of the development, or in the adult life, depending on the recessive or dominant autosomic component, respectively. In this review, the classification based on the functional disorder of the bone cell is discussed, as well as the main clinical and radiological characteristics than permit a simple and applicable diagnostic approach in the clinical practice.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Revista Colombiana de Reumatología - Volume 16, Issue 1, March 2009, Pages 46-60
نویسندگان
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