The Effect of Psychological Distress on Medication Adherence in Persons With HIV Infection in Nigeria

BackgroundA high level of adherence to prescribed antiretroviral (ARV) regimens is required to achieve and maintain suppression of human immunodeficiency virus (HIV) replication and prevent drug resistance.ObjectiveThis study aimed to determine the possible relationship between psychopathology and ARV medication adherence in Nigeria.MethodPersons with HIV infection (N = 182) completed various questionnaires on sociodemographic and clinical details, general psychopathology, self-esteem, and medication adherence.ResultsLow medication adherence was reported in 26.9% of the participants; significant correlates included presence of psychopathology and perceived poor social support.ConclusionThe success of any intervention policy for HIV-infected persons in sub-Saharan Africa must consider both low level of medication adherence and its associated factors.