کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3390735 | 1592603 | 2008 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Measurement of Disease Activity and Damage in Sjögren's Syndrome
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
ایمونولوژی، آلرژی و روماتولوژی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Measurement of Disease Activity and Damage in Sjögren's Syndrome Measurement of Disease Activity and Damage in Sjögren's Syndrome](/preview/png/3390735.png)
چکیده انگلیسی
Sjögren's syndrome (SS) is a systemic autoimmune disease that is characterized by an aggressive autoimmune response to epithelia, with consequent reduction of their secretions accompanied by sicca complaints. Systemic features may also be present in a subset of patients and may require more aggressive therapies. Improvements in knowledge concerning disease pathophysiology, combined with the availability of specifically targeted therapies able to modulate or block some of the most important pathologic mechanisms of the disease, may open totally new perspectives in the therapeutic approach to SS. The absence of reliable and validated outcome measures for SS is a major obstacle in performing clinical trials of new therapies in SS but studies devoted to defining outcome measurement instruments for this disorder have been performed or are in an advanced phases of completion.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Rheumatic Disease Clinics of North America - Volume 34, Issue 4, November 2008, Pages 963-971
Journal: Rheumatic Disease Clinics of North America - Volume 34, Issue 4, November 2008, Pages 963-971
نویسندگان
Claudio MD,