کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3391174 1592645 2009 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Calcifilaxis
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی ایمونولوژی، آلرژی و روماتولوژی
پیش نمایش صفحه اول مقاله
Calcifilaxis
چکیده انگلیسی
Pathologically, this disease manifests as a small vessel vasculopathy in which there is mural calcification with intimal proliferation, fibrosis and eventually thrombosis of the affected vessel, resulting in ischemia of the irrigated tissue. Clinically, the disease manifests by subcutaneous nodules and extremely painful violet, purple or ecchymosis plaques, over a mottled or reticular erythema similar to livedo reticularis. In a few days these lesions progress to the formation of necrotic ulcers covered with black eschar. The diagnosis is suspected on the basis of history taking and physical examination. Therapeutic measures are ineffective and should be directed at controlling phosphorus and calcium and standardizing calcium x phosphorus product is< 55mg/dl. The use of active vitamin D metabolites should be avoided.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminarios de la Fundación Española de Reumatología - Volume 10, Issue 4, October–December 2009, Pages 124-127
نویسندگان
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