کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3392943 1221304 2015 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Evaluation of eosinophilia in immigrants in Southern Spain using tailored screening and treatment protocols: A prospective study
ترجمه فارسی عنوان
ارزیابی ائوزینوفیلیا در مهاجران در جنوب اسپانیا با استفاده از پروتکل های غربالگری و درمان: یک مطالعه آینده نگر
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروبیولوژی و بیوتکنولوژی کاربردی
چکیده انگلیسی

SummaryObjectiveTo determine the etiology of eosinophilia in immigrant patients in Southern Spain.MethodsProspective study of immigrant patients with eosinophilia (>500 Eo/μL) attended in a reference Tropical Medicine Unit and evaluated through the implementation of a specific protocol structured in different levels meant to be accomplished depending on the findings of each previous level.ResultsOut of the 549 patients included in the study (89.6% from sub-Saharan countries), a diagnosis of helminthiasis was reached in 417 (75.9%), mainly by Strongyloides stercoralis (n = 190), Schistosoma (n = 33) and Hookworms (n = 126). 30 patients (5.5%) had a non-parasitic disorder (asthma, allergic rhinoconjunctivitis, skin conditions and drug-related eosinophilia). Multiple helminthic infections were very common: in 107 patients (19.5%) 2 helminth species were identified, three in 21 patients (3.8%), and four or more in 6 patients (1.1%). Eosinophilia was resolved in 31 of the 33 patients (93.9%) who received empirical treatment with ivermectin, albendazole and praziquantel as an etiological diagnosis was not reached after applying the whole protocol.ConclusionsDiagnosis of helminthic infections in immigrant patients with eosinophilia can be improved by using tailored protocols based on geographical exposure. The implementation of these protocols may also save costs by systematizing diagnostic explorations. Empirical treatment with ivermectin, albendazol and praziquantel in sub-Saharan population when an etiologic diagnosis of eosinophilia has not been attained is an effective measure.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Travel Medicine and Infectious Disease - Volume 13, Issue 4, July–August 2015, Pages 315–321
نویسندگان
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