Acute Hepatitis and Personality Change in a 31-Year-Old Man Taking Prohormone Supplement SUS500

BackgroundFor decades, anabolic-androgenic steroids have been abused to enhance muscle growth. The harm inflicted by these compounds is well documented.ObjectiveThe authors investigated and report on a case in which a male patient self-prescribed some newer dietary supplements, about which less is known.MethodThe authors report on a case of hepatitis and aggressive personality changes in a 31-year-old man taking purported prohormone agent SUS500 and other, newer supplements.ResultsDiagnosis was based on history, mental status exam, and laboratory findings. With discontinuation of all supplements and supportive care, the patient’s personality changes resolved, and normal liver function returned.ConclusionThe authors conclude that newer anabolic supplements may cause some of the same side effects as traditional steroid hormones.