کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3405774 1223482 2013 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Vancomycin in the treatment of meticillin-resistant Staphylococcus aureus (MRSA) infection: End of an era?
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروبیولوژی و بیوتکنولوژی کاربردی
پیش نمایش صفحه اول مقاله
Vancomycin in the treatment of meticillin-resistant Staphylococcus aureus (MRSA) infection: End of an era?
چکیده انگلیسی

Infection with meticillin-resistant Staphylococcus aureus (MRSA) continues to have significant morbidity and mortality. Vancomycin, which has been the mainstay of treatment of invasive MRSA infections, has several drawbacks related to its pharmacological properties as well as varying degrees of emerging resistance. These resistant subpopulations are difficult to detect, making therapy with vancomycin less reliable. The newer agents such as linezolid, daptomycin, ceftaroline, and the newer glycopeptides telavancin and oritavancin are useful alternatives that could potentially replace vancomycin in the treatment of certain conditions. By summarising the discussions that took place at the III MRSA Consensus Conference in relation to the current place of vancomycin in therapy and the potential of the newer agents to replace vancomycin, this review focuses on the challenges faced by the laboratory and by clinicians in the diagnosis and treatment of MRSA infections.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Global Antimicrobial Resistance - Volume 1, Issue 1, March 2013, Pages 23–30
نویسندگان
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