کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3410098 1224052 2014 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Rapid point of care diagnostic tests for viral and bacterial respiratory tract infections—needs, advances, and future prospects
ترجمه فارسی عنوان
نقطه سریع تست تشخیصی مراقبت از عفونت های دستگاه تنفسی باکتریایی و باکتری نیاز، پیشرفت و چشم انداز آینده
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی و میکروب شناسی (عمومی)
چکیده انگلیسی

SummaryRespiratory tract infections rank second as causes of adult and paediatric morbidity and mortality worldwide. Respiratory tract infections are caused by many different bacteria (including mycobacteria) and viruses, and rapid detection of pathogens in individual cases is crucial in achieving the best clinical management, public health surveillance, and control outcomes. Further challenges in improving management outcomes for respiratory tract infections exist: rapid identification of drug resistant pathogens; more widespread surveillance of infections, locally and internationally; and global responses to infections with pandemic potential. Developments in genome amplification have led to the discovery of several new respiratory pathogens, and sensitive PCR methods for the diagnostic work-up of these are available. Advances in technology have allowed for development of single and multiplexed PCR techniques that provide rapid detection of respiratory viruses in clinical specimens. Microarray-based multiplexing and nucleic-acid-based deep-sequencing methods allow simultaneous detection of pathogen nucleic acid and multiple antibiotic resistance, providing further hope in revolutionising rapid point of care respiratory tract infection diagnostics.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 14, Issue 11, November 2014, Pages 1123–1135
نویسندگان
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