کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3445782 1595349 2006 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Body Mass Index and Risk for Oral Contraceptive Failure: A Case–Cohort Study in South Carolina
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
پیش نمایش صفحه اول مقاله
Body Mass Index and Risk for Oral Contraceptive Failure: A Case–Cohort Study in South Carolina
چکیده انگلیسی

PurposeStudies have suggested that obesity is associated with an increased risk for oral contraceptive (OC) failure. We conducted a case–cohort study in South Carolina to examine the association between body mass index (BMI) and OC failure by using population-based data sources.MethodsOur cohort sample from the source population consists of 205 women who reported using OCs to prevent pregnancy on the 1999 Behavioral Risk Factor Surveillance System survey. The 153 women who reported using OCs at the time of conception on the 2000 Pregnancy Risk Assessment Monitoring System survey represent the case sample that arose from the source population. Logistic regression was used to obtain odds ratios (ORs) and 95% confidence intervals (CIs).ResultsIn unadjusted models with normal BMI (20 to 24.9 kg/m2) as the comparison, greater BMI was associated significantly with OC failure (overweight [25 to 29.9 kg/m2], OR = 2.54; 95% CI, 1.18–5.50; and obese [≥30 kg/m2], OR = 2.82; 95% CI, 1.05–7.58). After adjustment for education, income, and race/ethnicity, associations were attenuated and no longer statistically significant.ConclusionsIn this heterogeneous population, we found a suggestion that overweight and obese women may be at increased risk for OC failure. However, long-term prospective studies are needed to study this association in diverse populations.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Annals of Epidemiology - Volume 16, Issue 8, August 2006, Pages 637–643
نویسندگان
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