کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3446289 1595455 2016 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Low Thyroid Stimulating Hormone Levels Are Associated with Low Bone Mineral Density in Femoral Neck in Elderly Women
ترجمه فارسی عنوان
سطح هورمون های تحریک کننده پایین تریروئید همراه با تراکم استخوانی کم استخوانی در گردن فمورال در زنان سالمند
کلمات کلیدی
تراکم معدنی استخوان، سالمندان زن پوکی استخوان، هورمون تحریک کننده تیروئید
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
چکیده انگلیسی

Background and AimsTo determine the relationship between thyroid stimulating hormone (TSH) and bone mineral density (BMD) in elderly women.MethodsThis is a retrospective cross-sectional population cohort study of women aged ≥65 years. All 1097 subjects had no overt thyroid dysfunction, 47 had subclinical hyperthyroidism and 100 had subclinical hypothyroidism. Overall, 167 had normal BMD, 594 had osteopenia and 336 had osteoporosis.ResultsThe femoral neck (FN) BMD was lower in women with lower TSH, with a high prevalance of osteoporosis and osteopenia (p = 0.036).The prevalence of osteoporosis and osteopenia was significantly low in the lowest quartile compared with the third quartile (p = 0.023) and the fourth quartile (p = 0.002), and the second low quartile, compared with the fourth quartile (p = 0.028). The differences were not significant among subclinical hyperthyroid, subclinical hypothyroid and euthyroid women. Low TSH was related to low BMDs at FN by multiple logistic regression analysis corrected for age and BMI. TSH in the lower two quartiles were independently related to osteoporosis (OR: 1.960, p = 0.023 and OR: 1.800, p = 0.037) and osteopenia (OR: 2.108, p = 0.005 and OR: 1.723, p = 0.030). Low TSH quartile (β: 0.007, p = 0.013) predicting low BMDs at FN.ConclusionLow TSH was independently related to decreased BMDs at FN in elderly women without overt thyroid dysfunction.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Archives of Medical Research - Volume 47, Issue 4, May 2016, Pages 310–314
نویسندگان
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