کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3446455 1595464 2015 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Associated Risk Factors for Latent Tuberculosis Infection in Subjects with Diabetes
ترجمه فارسی عنوان
عوامل خطرساز مرتبط با عفونت سل خارج رحمی در افراد مبتلا به دیابت
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
چکیده انگلیسی

Background and AimsType 2 diabetes mellitus (DM2) confers a higher risk for active tuberculosis (TB). However, information on associated risk factors for latent tuberculosis infection (LTBI) inpatients with DM2 is limited. We conducted a cross-sectional study to elucidate the prevalence of LTBI and its associated factors on Mexican adults with DM2 receiving medical care at the Mexican Social Security Institute (IMSS).MethodsSix hundred patients with DM2 without a prior history of TB from outpatient diabetes clinics were enrolled in the study. The tuberculin-skin-test (TST) was performed. The presence of LTBI was defined by a TST value of ≥5 mm. A standardized interview and physical examination were conducted to obtain clinical, demographic, and LTBI risk factor information; all subjects were laboratory tested to determine the presence of exclusion criteria. Microscopic examination of sputum samples and chest x-rays was performed to identify potential active TB. Subjects with any finding suggesting active TB or malignancy were excluded. A logistic regression model was used to identify variables associated with LTBI.ResultsLTBI prevalence among patients with DM2 was 51.3%. Risk factors for LTBI were living with a relative with TB, having been in prison, having hemoglobin values >14 g/dL, and glycosylated hemoglobin (HbA1c) values of >7%. Blood pressure, economic income, or anthropometric measurements were not associated risk factors.ConclusionsOver one half of patients with DM harbor LTBI. Exposure to certain environmental conditions and poorly controlled DM2 (HbA1c >7.0%) were risk factors for having LTBI in persons with DM2.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Archives of Medical Research - Volume 46, Issue 3, April 2015, Pages 221–227
نویسندگان
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