کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3446880 1595481 2013 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Clinical Determinants of Health-related Quality of Life in Mexican Patients with Parkinson’s Disease
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
پیش نمایش صفحه اول مقاله
Clinical Determinants of Health-related Quality of Life in Mexican Patients with Parkinson’s Disease
چکیده انگلیسی

Background and AimsParkinson’s disease (PD) is the second most common chronic neurodegenerative disorder. PD is clinically characterized by a constellation of motor and nonmotor symptoms that may have a direct effect on daily activities as well as in the quality of life of the patient. Identifying the symptoms more closely associated with a poor quality of life is central on improving the medical care of the patient. We undertook this study to identify and describe the clinical and demographic factors that predict health-related quality of life among Mexican patients with PD.MethodsOne hundred seventy-seven patients with Parkinson’s disease were included. Patients were evaluated using the following clinimetric instruments: motor subscale of the Unified Parkinson’s disease rating scale, Hoehn and Yahr stage, Non-motor Symptoms Questionnaire, Parkinson’s disease Questionnaire (PDQ-39) and the Mini Mental Status Examination.ResultsMultivariate analysis showed that the main factors associated with a poor quality of life were motor impairment (β = 0.27, p <0.001) and the number of nonmotor symptoms (β = 2.17, p <0.001). The main nonmotor domains impacting on the quality of life were depression/anxiety (β = 6.36, p <0.001), cardiovascular (β = 5.39, p = 0.001), memory (β = 4.64, p <0.001) and miscellaneous (β = 3.15, p = 0.001).ConclusionsBoth motor and mainly nonmotor symptoms are negatively associated with health-related quality of life in patients with PD and should be appropriately attended in order to improve patient care.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Archives of Medical Research - Volume 44, Issue 2, February 2013, Pages 110–114
نویسندگان
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