کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3447590 1595513 2009 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Expression of CDllc in Blood Monocytes as Biomarker for Favorable Response to Antituberculosis Treatment
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
پیش نمایش صفحه اول مقاله
Expression of CDllc in Blood Monocytes as Biomarker for Favorable Response to Antituberculosis Treatment
چکیده انگلیسی

CD11c is involved in Mycobacterium tuberculosis phagocytosis by human macrophages. CD11c has not been evaluated during antituberculosis (anti-TB) treatment. CD11c expression was evaluated on monocytes from peripheral blood leukocytes of pulmonary TB (PTB) patients and healthy controls by flow cytometry, whereas CD11c/Arg47Trp polymorphism was analyzed using polymerase chain reaction-restriction fragment length polymorphism. PTB patients had increased levels of CD11c on blood monocytes as compared to healthy controls. CD11c levels decreased in response to anti-TB treatment. CD11c/Arg47Trp polymorphism is not associated with PTB.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Archives of Medical Research - Volume 40, Issue 2, February 2009, Pages 128–131
نویسندگان
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