کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3450909 1595764 2009 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A Study of Bone Mineral Density in Adults With Disability
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
پیش نمایش صفحه اول مقاله
A Study of Bone Mineral Density in Adults With Disability
چکیده انگلیسی

Smith ÉM, Comiskey CM, Carroll ÁM. A study of bone mineral density in adults with disability.ObjectivesTo examine prevalence of low bone mineral density (BMD) among adults with disability, using World Health Organization diagnostic categories.DesignCross-sectional study.SettingNational Rehabilitation Hospital, Dublin, Ireland.ParticipantsPatients (N=255; 178 men, 77 women) who were disabled for at least 3 months because of acquired brain injury, spinal cord injury, other neurologic condition, or lower-limb amputation.InterventionsNone.Main Outcome MeasuresLaboratory investigations including intact parathyroid hormone, 25-hydroxyvitamin D (25-OHD), and sex hormones; and BMD of lumbar spine and at least 1 hip, measured by dual-energy x-ray absorptiometry and expressed as T scores and z scores.ResultsMean age ± SD of participants was 48.7±15.6 years. Vitamin D deficiency, 25-OHD level 50nmol/L or less, occurred in 154 (62.9%); insufficiency, a level between 51 and 72nmol/L, occurred in 36 (14.7%). Based on T scores, 108 participants (42.4%) had osteopenia, and 60 (23.5%) had osteoporosis. A z score of −1 or less but more than −2 occurred in 76 (29.8%); a further 52 (20.4%) had a z score of −2 or less. On multiple linear regression analysis, ambulatory status and duration of disability were independent predictors of BMD at neck of femur (β=.152, P=.007; β=−.191, P=.001, respectively) and total proximal femur (β=.170, P=.001; β=−.216, P<.001, respectively).ConclusionsOsteopenia and osteoporosis are very common in adults with disability participating in rehabilitation, compared with the general young adult population. Duration since onset of disability and mobility status are independent predictors of BMD at the hip. Bone health monitoring should form part of the long-term follow-up in adults with newly acquired disabilities.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Archives of Physical Medicine and Rehabilitation - Volume 90, Issue 7, July 2009, Pages 1127–1135
نویسندگان
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