کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3459879 1408579 2016 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
High uric acid level predicts left atrial thrombus or spontaneous echo contrast detected by transesophageal echocardiography: Meta-analysis and systematic review
ترجمه فارسی عنوان
سطح اسید اوریک بالا پیش بینی ترومبوس دهلیزی سمت چپ یا کنتراست اکو خودبخودی تشخیص داده شده توسط اکوکاردیوگرافی ترانسوفاژ: متاآنالیز و بررسی سیستماتیک
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
چکیده انگلیسی

BackgroundRecent observational studies have suggested that the patients with hyperuricemia have a higher risk of having left atrial thrombus (LATH) or left atrial spontaneous echo contrast (LASEC) by transesophageal echocardiography (TEE), while the ultimate predictive value of a high uric acid (UA) level on LATH/LASEC remained obscure.MethodsWe searched the PubMed and Cochrane clinical trials databases up to July 2015. Following screening the 369 initially identified studies, we analyzed six observational studies with 2381 patients.ResultsThe meta-analysis of these studies showed that an elevated serum UA level was associated with a higher likelihood of LATH/LASEC (OR = 1.59, 95%CI 1.13–2.23, P = 0.008), while significant differences exist among individual trials (P < 0.00001 and I2 = 85%). Sensitivity analysis failed to find any heterogeneity.ConclusionAn elevated UA level was associated with a higher risk of detecting a left atrial abnormality represented by LATH/LASEC.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chronic Diseases and Translational Medicine - Volume 2, Issue 1, March 2016, Pages 27–33
نویسندگان
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