کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3460783 1231326 2009 18 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Liver Disease, Coagulation Testing, and Hemostasis
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
پیش نمایش صفحه اول مقاله
Liver Disease, Coagulation Testing, and Hemostasis
چکیده انگلیسی

This article reviews the variety of coagulation testing abnormalities identified and the evidence demonstrating their lack of correlation with hemostasis and inability to predict bleeding for patients with liver disease. The article discusses the historical and incorrect evolution of the commonly used “1.5×” prothrombin time/international normalized ratio “threshold” for fresh frozen plasma/frozen plasma (FFP/FP) administration. Finally, this article reviews why FFP/FP cannot correct minimally prolonged clotting times in patients with liver disease, nor provide adequate prophylaxis against bleeding from percutaneous liver biopsy.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinics in Laboratory Medicine - Volume 29, Issue 2, June 2009, Pages 265–282
نویسندگان
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