کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3468270 1596586 2010 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Under-recognized renal insufficiency in hospitalized patients: Implications for care
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
پیش نمایش صفحه اول مقاله
Under-recognized renal insufficiency in hospitalized patients: Implications for care
چکیده انگلیسی

BackgroundThe consequences of undetected low glomerular filtration rate (GFR) are important in hospitalized patients who receive potentially nephrotoxic drugs or undergo major surgery. This study estimated the prevalence of estimated GFR (eGFR) < 60 mL/min/1.73 m2 in hospitalized patients.MethodsThis cross-sectional descriptive study included 14,658 adults hospitalized at 10 centers in Spain. Serum samples were analyzed for hemoglobin, creatinine, albumin and urea nitrogen. eGFR was estimated using Modification of Diet in Renal Disease (MDRD) 4 or MDRD IDMS, and MDRD 6 when serum albumin and BUN were included (n = 8611). Individuals were classified as having GFR ≥ 60 mL/min/1.73 m2, stages 3, 4 and 5 (GFR 30–59, 15–29 and < 15 mL/min/1.73 m2, respectively). Additionally, stages 3a and 3b (GFR 45–59 and 30–44 mL/min/1.73 m2, respectively) were assessed.ResultsMDRD 4 eGFR showed that 28.3% of patients had renal insufficiency stages 3–5 and 14.2% had stages 3b, 4 or 5, which represents important-severe renal deterioration. Forty-three percent of patients with stages 3–5 had hemoglobin ≤ 11 g/dL, compared with 27.9% of patients with eGFR ≥ 60 mL/min/1.73 m2. A good correlation was observed between eGFR MDRD 4 and MDRD 6.ConclusionsA high percentage of hospitalized patients in Spain have deteriorated renal function stages 3–5. Using eGFR equations to assess eGFR could identify more hospitalized patients with renal insufficiency, potentially leading to improved care.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Internal Medicine - Volume 21, Issue 4, August 2010, Pages 327–332
نویسندگان
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