Seroprevalence of Toxoplasma gondii among pregnant women in Almadinah Almunawwarah KSA

ObjectivesGiven its detrimental obstetric and congential sequelae, the detection of primary toxoplasmosis is most critical during pregnancy. This study aims to detect the seroprevalence of Toxoplasma gondii (Toxoplasma gondii) among pregnant women who either have histories suggestive of toxoplasmosis or may be at risk.MethodsSerum samples of 150 pregnant women aged 18–45 years were tested by the rapid Toxoplasma test (TOXO IgM/IgG test, InTec). The results were further confirmed by the enzyme-linked immunosorbent assay (ELISA) technique for IgM and IgG.ResultsSerological results of toxoplasmosis seropositivity were statistically analyzed in light of the available epidemiological data. Thirty-two cases (21.3%) were IgG positive, and none was IgM positive, as shown by both tests.ConclusionSignificant relations were observed between seropositivity, maternal age and history of abortion, and probability of delivering a child with a congenital anomaly. Despite the lack of evidence of recent infection in this study, the high rates of T. gondii seropositivity among pregnant women signaled a threat of primary exposure during pregnancy.