کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3484419 1233743 2015 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Drug-induced immune thrombocytopenia associated with use of tyrosine kinase inhibitor imatinib
ترجمه فارسی عنوان
ترومبوسیتوپنی ایمنی ناشی از مواد مخدر همراه با استفاده از مهارکننده تیروزین کیناز ایاتینیب
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
چکیده انگلیسی

Since their introduction in the late 1990s, tyrosine kinase Inhibitors (TKIs) have been widely used for the treatment of various cancers. The side effects of the TKI imatinib are well-documented in the literature and include fatigue, skin rash, myelosuppression, and derangement of liver enzymes. Rare side effects have been observed in the postmarketing surveillance and include cardiac tamponade and Steven Johnson Syndrome. In the present report, we present a rare case of imatinib-associated immune thrombocytopenia leading to severe intra-abdominal bleeding. A brief account of similar cases of TKI drug-induced immune thrombocytopenia (DIT) is also described.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Taibah University Medical Sciences - Volume 10, Issue 3, September 2015, Pages 365–368
نویسندگان
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