کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
35326 | 45086 | 2008 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Production and statistical optimization of a novel olivanic acid by Streptomyces olivaceus MTCC 6820
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Production and statistical optimization of a novel olivanic acid by Streptomyces olivaceus MTCC 6820 Production and statistical optimization of a novel olivanic acid by Streptomyces olivaceus MTCC 6820](/preview/png/35326.png)
چکیده انگلیسی
A microbial strain, isolated from soil samples, characterized as Streptomyces olivaceus MTCC 6820 showed broad-spectrum antibacterial activity. The compound produced was chemically characterized as a new form of olivanic acid. Olivanic acid production was optimized statistically by Plackett-Burman design (PBD) and response surface methodology (RSM). Effects of soybean meal, glycerol, CaCO3 and dl-alanine were investigated with the help of PBD. The individual and interaction effects of the studied variables were evaluated by RSM using central composite design (CCD). By applying statistical design, antibiotic production was enhanced nearly 8 times (415 mg/l) as compared with the normal production medium (50 mg/l).
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Process Biochemistry - Volume 43, Issue 11, November 2008, Pages 1313–1317
Journal: Process Biochemistry - Volume 43, Issue 11, November 2008, Pages 1313–1317
نویسندگان
Vineeta Singh, C.K.M. Tripathi,