Haemostasis

Haemostasis involves an explosive reaction, designed to curtail blood loss, restore vascular integrity, provide a barrier to infection, and ultimately preserve life. Haemostatic balance is maintained through four key components – vascular endothelium, platelets, coagulation pathway and fibrinolysis. Any imbalance in this tightly regulated process can result in thrombotic or haemorrhagic conditions with associated morbidity and mortality.