Pharmacokinetics for the prescriber

Pharmacokinetics is the science that describes (using the ADME approach) the absorption of a drug from its site of administration, its distribution throughout the body, its metabolism or conjugation, and its excretion from the body. Pharmacokinetics can be thought of as what the body does to the drug. This article describes the basic principles and outlines how an understanding of pharmacokinetics can support rational prescribing.