Chemotherapy and radiotherapy for colorectal cancers

Surgery remains the cornerstone of the curative treatment of localized colorectal cancer (CRC), but both radiotherapy and chemotherapy play an important role in the management of these patients to help improve survival. Treatment of locally advanced and metastatic disease often requires multimodality therapy. Advances in both surgical techniques and non-surgical oncology have led to a reduction in the mortality rate over the last 40 years.