کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3839214 | 1247773 | 2011 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Kidney transplantation
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
پزشکی و دندانپزشکی (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Kidney transplantation Kidney transplantation](/preview/png/3839214.png)
چکیده انگلیسی
Renal transplantation is the optimal form of renal replacement therapy, and should be considered in all patients with end stage renal failure. It is effective and cost-effective. Kidneys can be obtained from living donation or deceased donation (either after brain death or after circulatory death). Immunosuppression is required for the life of the allograft to prevent rejection. A typical regimen comprises an induction agent (either an IL-2 or CD52 receptor antagonist) and maintenance triple therapy (calcineurin inhibitor, anti-proliferative agent and steroids). Retrieval of the kidneys from a deceased donor is performed as part of the multi-organ retrieval process. Living donor nephrectomy can be performed laparoscopically or open. A number of risks are attached to the transplant operation, but generally outcomes are good. New approaches to shorten waiting lists for renal transplantation include paired-exchange programmes, domino transplants and transplantation across ABO or HLA boundaries.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Surgery (Oxford) - Volume 29, Issue 7, July 2011, Pages 330-335
Journal: Surgery (Oxford) - Volume 29, Issue 7, July 2011, Pages 330-335
نویسندگان
Nicholas Barnett, Nizam Mamode,