Fetal Neuroimaging of Neural Migration Disorder

Prenatal diagnosis of migration disorder is among the most difficult challenges of an antenatal sonographic examination. Anterior coronal demonstration of the sylvian fissures is recommended as the screening of cortical development and maldevelopment. Once suspicion of a migration disorder develops, MR imaging is the preferred modality for demonstration of cortical development. Considering that migration disorders occur before fetal viability but detection of brain lesions is most commonly performed in the third trimester, this presents a diagnostic dilemma. Early detection of migration disorder with severe prognosis is among the central missions of fetal neuroimaging.