کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3846326 1248318 2014 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Treatment of ANCA-Associated Vasculitis: New Therapies and a Look at Old Entities
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های کلیوی
پیش نمایش صفحه اول مقاله
Treatment of ANCA-Associated Vasculitis: New Therapies and a Look at Old Entities
چکیده انگلیسی
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a small-vessel vasculitis that primarily comprises 2 clinical syndromes: granulomatosis with polyangiitis and microscopic polyangiitis. Cyclophosphamide and glucocorticoids have traditionally been used for induction of remission. However, more recent studies have shown that rituximab is as effective as cyclophosphamide for induction therapy in patients with newly diagnosed severe AAV and superior for patients with relapsing AAV. There is also accumulating evidence indicating a potential role of rituximab for maintenance therapy in AAV. In this article, we will review the evidence supporting the various treatment choices for patients with AAV.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Advances in Chronic Kidney Disease - Volume 21, Issue 2, March 2014, Pages 182-193
نویسندگان
, , , ,