کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3847947 | 1598264 | 2014 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Bile Acid Nephropathy in a Bodybuilder Abusing an Anabolic Androgenic Steroid
ترجمه فارسی عنوان
نفروپاتی اسید روغنی در بدنسازان سوء استفاده از استروئید آندروژنی آنابولیک
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کلمات کلیدی
نفروپاتی اسید صفرا، آسیب حاد کلیه، زردی کلستاتیک،
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
بیماریهای کلیوی
چکیده انگلیسی
Bile acid nephropathy, also known as cholemic nephrosis or nephropathy, is an entity that can be seen in patients with severe cholestatic liver disease. It typically is associated with acute kidney injury (AKI) with various forms of hepatic disease. Most often, patients with severe obstructive jaundice develop this lesion, which is thought to occur due to direct bile acid injury to tubular cells, as well as obstructing bile acid casts. Patients with end-stage liver disease also can develop AKI, in which case a more heterogeneous lesion occurs that includes hepatorenal syndrome and acute tubular injury/necrosis. In this circumstance, acute tubular injury develops from a combination of hemodynamic changes with some contribution from direct bile acid-related tubular toxicity and obstructive bile casts. We present a case of AKI due to bile acid nephropathy in a bodybuilder who developed severe cholestatic liver disease in the setting of anabolic androgenic steroid use.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: American Journal of Kidney Diseases - Volume 64, Issue 3, September 2014, Pages 473-476
Journal: American Journal of Kidney Diseases - Volume 64, Issue 3, September 2014, Pages 473-476
نویسندگان
Randy L. MD, PhD, Ekaterina MD, Gilbert MD, PhD, Mark A. MD,