کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3848291 1598277 2013 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
AA Amyloidosis Associated With Systemic-Onset Juvenile Idiopathic Arthritis
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های کلیوی
پیش نمایش صفحه اول مقاله
AA Amyloidosis Associated With Systemic-Onset Juvenile Idiopathic Arthritis
چکیده انگلیسی
We report a 12-year-old boy with nephrotic syndrome due to renal AA amyloidosis. The AA amyloidosis was associated with a 3-year history of systemic-onset juvenile idiopathic arthritis. The presence of serum amyloid A protein was confirmed by laser microdissection of Congo Red-positive glomeruli and vessels followed by liquid chromatography and tandem mass spectrometry; this analysis excluded hereditary and familial amyloidosis. Aggressive management of the systemic-onset juvenile idiopathic arthritis resulted in improvement in clinical and laboratory parameters. The case represents an unusual cause of nephrotic syndrome in children. Early diagnosis of renal amyloidosis and management of systemic-onset juvenile idiopathic arthritis is paramount to preventing progression of kidney disease.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: American Journal of Kidney Diseases - Volume 62, Issue 4, October 2013, Pages 834-838
نویسندگان
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