Changes in Left Ventricular Diastolic Function During Hemodialysis Sessions

Left ventricular diastolic function worsens early during a hemodialysis session. The decrease in mean e′ at 60 minutes intradialysis was unrelated to changes in relative blood volume. Although this finding does not exclude a role of hypovolemia because of the limitations of the measurement of relative blood volume, it raises the possibility that non-volume-related mechanisms are involved in the early decrease in mean e′ during hemodialysis.