کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3897269 1250248 2008 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The Future of Pediatric Acute Kidney Injury Management-Biomarkers
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های کلیوی
پیش نمایش صفحه اول مقاله
The Future of Pediatric Acute Kidney Injury Management-Biomarkers
چکیده انگلیسی
Acute kidney injury (AKI) represents a common and devastating problem in clinical medicine. A major reason is the lack of early biomarkers for AKI, and hence an unacceptable delay in initiating therapy. Fortunately, the application of innovative technologies has uncovered several novel biomarkers. The most promising of these are included in a putative AKI biomarker panel, consisting of neutrophil gelatinase-associated lipocalin, interleukin-18, and kidney injury molecule-1. These biomarkers have completed initial validation, and have entered the prospective screening stage in the biomarker development process, facilitated by the development of commercial tools for their reproducible measurement across laboratories. The availability of a panel of validated biomarkers will revolutionize renal and critical care, and enable the practice of personalized and predictive medicine at an unprecedented level.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminars in Nephrology - Volume 28, Issue 5, September 2008, Pages 493-498
نویسندگان
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