کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3897501 | 1250258 | 2010 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Integrative Analysis of -Omics Data and Histologic Scoring in Renal Disease and Transplantation: Renal Histogenomics
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
بیماریهای کلیوی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Integrative Analysis of -Omics Data and Histologic Scoring in Renal Disease and Transplantation: Renal Histogenomics Integrative Analysis of -Omics Data and Histologic Scoring in Renal Disease and Transplantation: Renal Histogenomics](/preview/png/3897501.png)
چکیده انگلیسی
The histologic scoring of renal biopsies is still the gold standard for renal disease classification. The Banff classification scheme and the chronic allograft damage index are histopathologic scoring schemes widely used in renal transplantation. The determination of genome-wide gene expression profiles in human renal biopsies has the potential to serve as independent validation data sets and also provide a more precise evaluation of the functional status behind the visible morphologic alterations. It is expected that results from high-throughput -omics experiments will lead to improved classification schemes in the near future as also discussed at recent Banff meetings. In this review we give an overview on -omics studies, focusing on the association of molecular changes on the transcript as well as on the protein level and morphologic scoring schemes in renal disease and transplantation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminars in Nephrology - Volume 30, Issue 5, September 2010, Pages 520-530
Journal: Seminars in Nephrology - Volume 30, Issue 5, September 2010, Pages 520-530
نویسندگان
Paul PhD, Rainer MD, MSc,