A modular approach for multicomponent synthesis of amidines using modified Scolecite

• Copper exchanged Scolecite(Cu-Scolecite) was prepared by ion exchange method.
• The catalytic activity of Cu-Scolecite was evaluated for multi-component synthesis of amidines.
• High yields with easy recovery and reusability of catalyst were observed.

Copper exchanged Scolecite was successfully synthesized and used as an efficient, mild and recyclable catalyst for promoting multi-component synthesis of amidines from 4-toluenesulfonyl azide, phenyl acetylene and variety of substituted amines in THF at ambient temperature in good yields within short reaction time.

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