کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3910174 | 1251245 | 2007 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Disseminated tumor cells: Are they ready for clinical use?
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Disseminated tumor cells: Are they ready for clinical use? Disseminated tumor cells: Are they ready for clinical use?](/preview/png/3910174.png)
چکیده انگلیسی
During the past three decades, efforts successfully established the presence of disseminated tumor cells (DTC) in bone marrow as a prognostic factor. These works were comprehensively evaluated in a pooled analysis that now permits to classify the prognostic significance of DTC as level I evidence. Intriguing molecular data suggest a role for tumor stem cells possibly responsible for the prognostic impact of DTC. In a typical clinical setting of the year 2007, DTC—irrespectively of the strong prognostic significance—would only have a convincing clinical application if DTC were a surrogate marker for treatment efficacy. Consequently, this important question is to be addressed in well-designed clinical trials.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Breast - Volume 16, Supplement 2, 2007, Pages 51–54
Journal: The Breast - Volume 16, Supplement 2, 2007, Pages 51–54
نویسندگان
Stephan Braun, Florian D. Vogl, Alois Schneitter, Daniel Egle, Doris Auer, Margarete Lang, Christian Marth,