کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3915470 1251509 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Mifepristone versus laminaria: a randomized controlled trial of cervical ripening in midtrimester termination
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
Mifepristone versus laminaria: a randomized controlled trial of cervical ripening in midtrimester termination
چکیده انگلیسی

BackgroundMifepristone was compared with laminaria for cervical ripening in second-trimester induction of labor (IOL).Study DesignWe performed a randomized, controlled, open-label study of women undergoing second-trimester IOL for fetal demise, aneuploidy or anomalies at a single tertiary care center from January 2004 to May 2006. Main outcome measures were induction-to-delivery time and pain with cervical ripening.ResultsOf 50 eligible women, 37 were enrolled in the study, of whom 33 completed the study: 16 were randomized to laminaria and 17 to mifepristone. Induction-to-delivery time was significantly shorter in the mifepristone arm (mean=10 h vs. 16 h, p=.01; median=7.5 h vs. 13.4 h, p=.01). Pain with cervical ripening was also significantly less in the mifepristone group than in the laminaria group (median=1 vs. 6 on an 11-point visual analogue scale, p<.001). Maternal age, parity, gestational age, fetal demise prior to induction, need for postpartum curettage, blood loss, pain during induction, delivery and at the time of discharge were not significantly different between the two groups.ConclusionMifepristone shortens the induction-to-delivery time and decreases pain with cervical ripening when compared with laminaria for second-trimester induction.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Contraception - Volume 76, Issue 5, November 2007, Pages 383–388
نویسندگان
, , , , , ,