کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3919841 | 1599811 | 2013 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: The value of serum albumin as a novel independent marker for prognosis in patients with endometrial cancer The value of serum albumin as a novel independent marker for prognosis in patients with endometrial cancer](/preview/png/3919841.png)
ObjectiveHypoalbuminemia, a known marker for malnutrition and increased morbidity and mortality, has been associated with impaired prognosis in different cancer entities. The present study investigates the prognostic value of pre-treatment serum albumin levels for survival in patients with endometrial cancer.Study designWithin the present cohort study, we evaluated 337 consecutive patients with endometrial cancer and investigated the association of pre-treatment serum albumin levels and clinical-pathological parameters. We performed univariate log-rank tests and multivariable Cox regression models to assess the association between pre-treatment serum albumin levels and survival.ResultsPre-treatment serum albumin levels were inversely proportionally associated with FIGO tumor stage, histological grade, and patients’ age. In a multivariable analysis pre-treatment serum albumin levels (p = 0.02 and p = 0.001), FIGO tumor stage (p < 0.001 and p < 0.001), and histological grade (p = 0.002 and p < 0.001) were independently associated with disease-free and progression-free survival, respectively.ConclusionPre-treatment serum albumin is a novel and independent prognostic parameter for disease-free and progression-free survival in patients with endometrial cancer.
Journal: European Journal of Obstetrics & Gynecology and Reproductive Biology - Volume 171, Issue 1, November 2013, Pages 101–106