کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3920067 1599805 2014 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The role of C-reactive protein measurement as a diagnostic aid in early pregnancy
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
The role of C-reactive protein measurement as a diagnostic aid in early pregnancy
چکیده انگلیسی

ObjectiveTo investigate the values of C-reactive protein (CRP) in early pregnancy for detection of any abnormality of the conceptus and especially the condition of extra-uterine pregnancy (EUP).Study designIn this prospective observational study, we established reference values for CRP in early pregnancy. Next, we tested whether a single, wide-range CRP measurement could serve as a diagnostic tool for abnormal first trimester pregnancy by comparing CRP levels in three different pregnancy statuses: viable intrauterine pregnancy (Group A), EUP (Group B) and delayed abortion (Group C).ResultsCRP levels were significantly higher in normal pregnancy (Group A) compared to abnormal pregnancy (Group B + C and Group B alone). CRP level was influenced only by the pregnancy status (normal, EUP or delayed abortion) and not by age, BMI, hematocrit or gravidity. The multiple logistic regression model (adjusted for age, gravidity, gestational age, hematocrit and BMI) revealed CRP as being a predictor for normal intrauterine pregnancy.ConclusionThis study examined the association between CRP levels and abnormal first trimester pregnancies. Our results support single CRP measurement as a diagnostic tool in early pregnancy.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Obstetrics & Gynecology and Reproductive Biology - Volume 176, May 2014, Pages 64–67
نویسندگان
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