کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3922152 | 1599889 | 2007 | 6 صفحه PDF | دانلود رایگان |
ObjectiveThis study aims to determine whether women with endometriosis have greater subclinical atherosclerosis than the general population.Study designThis case-control study included 66 women with endometriosis and 66 controls matched for age and body mass index. All subjects were ≥35 years old. Exclusion criteria were obesity, diabetes, hypertension, hyperlipidemia, renal or metabolic diseases. Before laparoscopy, all patients underwent a measurement of intima-media thickness (IMT) and distensibility coefficient (DC) on the common carotid artery. In addition, blood samples were taken to determine the levels of lipids, fibrinogen, C-reactive protein, homocysteine, fasting glycemia, antithrombin III, plasminogen, protein C, protein S, and activated protein C resistance.ResultsAll the biochemical parameters evaluated had similar levels in the two study groups. IMT was similar in women with endometriosis and in controls both on left (p = 0.330) and right (p = 0.648) carotid artery. Similarly, no significant difference was observed in the DC between women with endometriosis and controls both on left (p = 0.539) and right (p = 0.178) carotid artery. No significant difference was observed in IMT and DC between women with mild and severe endometriosis.ConclusionWomen with endometriosis do not have more subclinical atherosclerosis than the general population.
Journal: European Journal of Obstetrics & Gynecology and Reproductive Biology - Volume 132, Issue 2, June 2007, Pages 226–231