کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3927931 1253191 2007 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Holmium Laser Enucleation versus Transurethral Resection of the Prostate: 3-Year Follow-Up Results of a Randomized Clinical Trial
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
Holmium Laser Enucleation versus Transurethral Resection of the Prostate: 3-Year Follow-Up Results of a Randomized Clinical Trial
چکیده انگلیسی

ObjectivesTo report 3-yr follow-up results of a randomised clinical trial comparing holmium laser enucleation of the prostate (HoLEP) with transurethral resection of the prostate (TURP).MethodsA total of 200 patients with urodynamic obstruction and a prostate volume of less than 100 cc were prospectively randomised and assigned to HoLEP or TURP. All patients were assessed preoperatively and followed at 1, 6, 12, 18, 24, and 36 mo postoperatively. American Urological Association Symptom Score (AUA SS), maximum flow rate (Qmax), and postvoid residual (PVR) [urine] volume were obtained at each follow-up. Perioperative data and postoperative outcome were compared. All complications were recorded.ResultsAUA SS were significantly better 2 yr postoperatively in the HoLEP group (1.7 vs. 3.9, p < 0.0001) and similar at 3 yr (2.7 vs. 3.3, p = 0.17). PVR volume was significantly better 2 yr (5.6 vs. 19.9 ml, p < 0.001) and 3 yr (8.4 vs. 20.2 ml, p = 0.012) postoperatively in HoLEP patients. Qmax was similar in the HoLEP and TURP groups at 2 yr (28.0 vs. 29.1 ml/s, p = 0.83) and at 3 yr (29.0 vs. 27.5 ml/s, p = 0.41) postoperatively. Late complications consisted of urethral strictures, bladder-neck contractures, and BPH recurrence; reoperation rates were 7.2% in the HoLEP and 6.6% in the TURP group (p = 1.0).ConclusionsAfter 2 and 3 yr of follow-up, HoLEP micturition outcomes compare favourably with TURP. Late complications are equally low. HoLEP may be a real alternative to TURP.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Urology - Volume 52, Issue 5, November 2007, Pages 1456–1464
نویسندگان
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