کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3933841 1253363 2009 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Low-dose aspirin in non-tubal IVF patients with previous failed conception: a prospective randomized double-blind placebo-controlled trial
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
Low-dose aspirin in non-tubal IVF patients with previous failed conception: a prospective randomized double-blind placebo-controlled trial
چکیده انگلیسی

ObjectiveTo analyze whether the administration of low-dose aspirin during IVF treatment improves the uterine blood flow and improves ongoing pregnancy rates for non–tubal factor IVF patients with previous failed conception.DesignProspective double-blind placebo-controlled trial.SettingUniversity fertility clinic.Patient(s)Non-tubal IVF patients with previous failed conception.Intervention(s)Daily 100 mg aspirin or placebo throughout an IVF treatment with a long GnRH-agonist stimulation protocol.Main Outcome Measure(s)Ongoing pregnancy rate, pulsatility index of the uterine artery.Result(s)Of 169 patients, 84 were assigned to aspirin treatment and 85 to placebo treatment. In the aspirin group, 28 patients (35.4%) had an ongoing pregnancy, and in the placebo group, 26 patients (31.0%) had an ongoing pregnancy. Multilevel analyses showed that the pulsatility index of the uterine artery was not affected by aspirin or placebo treatment.Conclusion(s)Low-dose aspirin administration during IVF treatment does not improve pregnancy rates of non–tubal factor IVF patients with previous failed conception, and it does not affect the arterial uterine blood flow.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fertility and Sterility - Volume 92, Issue 3, September 2009, Pages 923–929
نویسندگان
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