کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3936551 | 1253453 | 2009 | 6 صفحه PDF | دانلود رایگان |
ObjectiveTo compare the clinical effects in women with cesarean scar pregnancy (CSP) who were treated with either methotrexate (MTX) regimen only or MTX regimen followed by dilation and curettage (D&C).DesignProspective consecutive clinical cohort study.SettingUniversity hospital for obstetrics, gynecology, and reproductive medicine.Subject(s)Seventy-one cases of CSP.Intervention(s)The subjects were treated with either MTX only (MTX group, 21 cases) or MTX followed by D&C (combined therapy group, 50 cases).Main Outcome Measure(s)Success rates, hysterectomy rates, and time to resolution of serum β-hCG and the CSP mass were compared between the two groups.Result(s)Compared with the MTX group, the combined therapy group had a shorter time to resolution of the CSP mass and serum β-hCG. There was no significant difference between the MTX and combined therapy groups regarding success rates (76.2% vs. 90.0%, respectively) and hysterectomy rates (19.0% vs. 8.0%, respectively).Conclusion(s)Both therapies could treat the majority of CSP patients successfully, but the combined therapy resulted in a shorter time of therapy and indicated a more favorable effect.
Journal: Fertility and Sterility - Volume 92, Issue 4, October 2009, Pages 1208–1213