کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3938340 1253528 2010 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Human papillomavirus found in sperm head of young adult males affects the progressive motility
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
Human papillomavirus found in sperm head of young adult males affects the progressive motility
چکیده انگلیسی

ObjectiveTo evaluate the prevalence of human papillomavirus (HPV) sperm infection and its correlation with sperm parameters in a cohort of young adult males.DesignCross-sectional clinical study.SettingAndrology and Microbiology sections at a university hospital.Patient(s)A cohort of 200 young adult male volunteers (18 years old), 100 with previous sexual intercourse and 100 without previous sexual intercourse.Main Outcome Measure(s)Seminal parameters, sperm culture for HPV and fluorescence in situ hybridization (FISH) analysis for HPV detection in the sperm head. Statistical analysis was performed with a two-tailed Student's t-test.Result(s)Results of HPV investigation were compared to sperm parameters and results of FISH analysis. HPV infection was present in sperm cells of 10 subjects among those 100 young adults who already had unprotected intercourse and its presence was associated with reduced sperm motility. Furthermore, infected samples showed that about 25% of sperm had an HPV DNA positivity at the head site, but it is unclear whether it was integrated in the nucleus or not.Conclusion(s)This is the first report estimating the percentage of HPV-positive sperm in infected subjects and the association between HPV infection and sperm motility.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fertility and Sterility - Volume 93, Issue 3, February 2010, Pages 802–806
نویسندگان
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