کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3941117 | 1253603 | 2006 | 6 صفحه PDF | دانلود رایگان |
ObjectiveTo assess the outcomes of patients who underwent uterine fibroid embolization (UFE) and to evaluate factors associated with failure of UFE.DesignRetrospective study.SettingUniversity teaching hospital.Patient(s)Two hundred thirty-three consecutive patients who underwent UFE from November 1997 to February 2004.Intervention(s)Uterine fibroid embolizations were performed by three interventional radiologists using 355–500-μ polyvinyl alcohol particles.Main Outcome Measure(s)Hysterectomy rate, myomectomy rate, and repeat UFE rate.Result(s)With a mean follow-up of 13 months, a total of 22 patients underwent surgery after UFE (9.4%); 16 had hysterectomies (6.9%), and 6 had myomectomies (2.6%). This included 3 patients who underwent repeat UFE and subsequently required surgical intervention. The mean (± SEM) time interval between UFE and subsequent treatment was 12.5 ± 2.0 months. Among patients who required surgery, 13 (59.1%) presented with recurrent menorrhagia, and 5 (22.7%) complained of persistent abdominal pain. Histopathologic examination revelead concomitant findings of adenomyosis in 25% of hysterectomy specimens. Patients who failed UFE were more likely to have had a previous myomectomy (13% vs. 2.4%) and significant reduction in the uterine size 6 months after UFE (57.1% vs. 25.2%).Conclusion(s)The overall failure rate of UFE is 9.4%. Failure is mainly due to persistent menorrhagia and abdominal pain. Shrinkage of the uterus after UFE does not necessarily correlate with long-term success of UFE.
Journal: Fertility and Sterility - Volume 85, Issue 1, January 2006, Pages 30–35