Effects of anti-TNF-mAb treatment on pregnancy in baboons with induced endometriosis

Medical inhibition of TNFα allowed for normal conception but did not improve fecundity in baboons with induced endometriosis when compared with placebo. Larger studies with clinically available TNFα blockers in baboons with moderate to severe endometriosis are needed to further test the potential of these agents in the prevention or treatment of endometriosis-associated subfertility.